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PRMT4-IN-3
SKU
HY-155154A-Get quote
Category Reference compound
Tags Cancer, Epigenetics, Histone Methyltransferase
Products Details
Product Description
– PRMT4-IN-3 (compound 56) is a potent inhibitor of class I protein arginine methyltransferase (PRMT), targeting PRMT4 (IC50: 37 nM) and PRMT4 (IC50: 253 nM)[1].
Web ID
– HY-155154A
Shipping
– Room temperature
Molecular Formula
– C23H29N7O
References
– [1]Bhattacharya D, et al. Development of selective class I protein arginine methyltransferase inhibitors through fragment-based drug design approach. Eur J Med Chem. 2023 Nov 15;260:115713..
Molecular Weight
– 419.52
SMILES
– O=C(N[C@H]1CN(CCNC)CC1)C2=CC3=NC=NC(NC4=CC=C(CN)C=C4)=C3C=C2
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.