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Pristinamycin
$250 – $1,350
Products Details
Product Description
– Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF)[1].
Web ID
– HY-A0279
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C73H89N11O17
References
– [1]Meng J, et al. Improvement of pristinamycin I (PI) production in Streptomyces pristinaespiralis by metabolic engineering approaches. Synth Syst Biotechnol. 2017;2(2):130-136. Published 2017 Jun 8.|[2]Maskell JP, et al. Comparative in-vitro activity of erythromycin, vancomycin and pristinamycin. Infection. 1988;16(6):365-370.|[3]Orfila J, Haider F. Action de la pristinamycine sur les Chlamydia [Action of pristinamycin on Chlamydia]. Pathol Biol (Paris). 1984;32(5):443-445.
CAS Number
– 270076-60-3
Molecular Weight
– 1392.55
Compound Purity
– 99.63
SMILES
– O=C(N[C@@H]1C(N[C@H](CC)C(N2[C@](CCC2)([H])C(N(C)[C@@H](CC3=CC=C(N(C)C)C=C3)C(N4[C@](CC(CC4)=O)([H])C(N[C@@H](C5=CC=CC=C5)C(O[C@@H]1C)=O)=O)=O)=O)=O)=O)C6=NC=CC=C6O.O=C7N8C(C(O[C@@H]([C@@H](/C=C/C(NC/C=C/C(C)=C/[C@H](CC(CC9=NC7=CO9)=O)O)=O)C)C(C)C)=O)=CCC8
Clinical Information
– Phase 4
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial
Pathway
– Anti-infection
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
