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Products Details
Product Description
– Pravastatin-d3 (sodium) is the deuterium labeled Pravastatin sodium salt. Pravastatin (CS-514) sodium salt is a competitive HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM[1][2].
Web ID
– HY-B0165CS
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H32D3NaO7
References
– [1]McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42(1):65-89.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1329836-90-9
Molecular Weight
– 449.53
SMILES
– O=C([C@H](CC)C([2H])([2H])[2H])O[C@H]1C[C@@H](C=C2[C@]1([C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC([O-])=O)O)O)[H])O.[Na+]
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Autophagy;HMG-CoA Reductase (HMGCR);Isotope-Labeled Compounds
Pathway
– Autophagy;Metabolic Enzyme/Protease;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
