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Products Details
Product Description
– Pravastatin-13C,d3 (sodium) is the 13C- and deuterium labeled Pravastatin (sodium). Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
Web ID
– HY-B0165AS
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22 13CH32D3NaO7
References
– [1]McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42(1):65-89.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.
Molecular Weight
– 450.52
SMILES
– O[C@](C[C@@H](O)CC(O[Na])=O)([H])CC[C@@H]1[C@@]2([H])[C@H](C[C@@H](C=C2C=C[C@@H]1C)O)OC([C@@H]([13C]([2H])([2H])[2H])CC)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease; Cancer
Solubility
– 10 mM in DMSO
Target
– Autophagy;Ferroptosis;HMG-CoA Reductase (HMGCR);Isotope-Labeled Compounds
Pathway
– Apoptosis;Autophagy;Metabolic Enzyme/Protease;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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