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Products Details
Product Description
– Pravastatin (CS-514) is a competitive HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM[1].
Web ID
– HY-B0165
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H36O7
Citations
– Front Cell Dev Biol. 2020 May 28;8:404.|Cell Syst. 2018 Apr 25;6(4):424-443.e7.|Front Cell Dev Biol. 2022 Mar 3;10:806081.|Research Square Preprint. 2022 Feb.
References
– [1]McTavish D, et al. Pravastatin. A review of its pharmacological properties and therapeutic potential in hypercholesterolaemia. Drugs. 1991 Jul;42(1):65-89.
CAS Number
– 81093-37-0
Molecular Weight
– 424.53
SMILES
– O[C@@H](C[C@@H](O)CC(O)=O)CC[C@@H]([C@H](C=C1)C)[C@@](C1=C[C@@H](O)C2)([H])[C@H]2OC([C@@H](C)CC)=O
Clinical Information
– Launched
Research Area
– Cardiovascular Disease; Cancer
Solubility
– 10 mM in DMSO
Target
– Autophagy;HMG-CoA Reductase (HMGCR)
Pathway
– Autophagy;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
