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Products Details
Product Description
– PptT-IN-3 (compound 5p) is a potent inhibitor of with phosphopantetheinyl phosphoryl transferase (PptT) an IC50 of 3.5 μM. Phosphopantetheinyl transferase, an essential enzyme that plays a critical role in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. PptT-IN-3 has the potential for the research of tuberculosis[1].
Web ID
– HY-115884
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H27N5O3S
References
– [1]Ottavi S, et al. In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas. J Med Chem. 2022 Feb 10;65(3):1996-2022.
Molecular Weight
– 369.48
SMILES
– CCNC(NC(NC1=C(C=C(C=C1CC)S(=O)(NCC)=O)CC)=O)=N
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
