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Products Details
Product Description
– PPARγ agonist 1 (compound 15) is a potent agonist of PPARγ. PPARγ agonist 1 shows high efficacy to activate hPPARγ without raising a full agonism and probably avoiding adverse effects. PPARγ agonist 1 has the potential for the research of cardiovascular diseases associated with metabolic disorders[1].
Web ID
– HY-146731
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C34H39NO3
References
– [1]Vila L, et al. Synthesis and biological studies of “Polycerasoidol” and “trans-δ-Tocotrienolic acid” derivatives as PPARα and/or PPARγ agonists. Bioorg Med Chem. 2022;53:116532.
Molecular Weight
– 509.68
SMILES
– C/C(CC/C=C(C(NC1=CC=CC=C1)=O)C)=CCCC2(CCC3=C(O2)C=CC(OCC4=CC=CC=C4)=C3)C
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– PPAR
Pathway
– Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
