Products Details

Product Description

– PPARγ agonist 8 is an agonist of PPARγ. PPARγ agonist 8 induces peroxisome proliferator response element (PPRE)-luciferase activity with an EC50 of 0.2 μM[1].

Web ID

– HY-153982

Shipping

– Room temperature

Molecular Formula

– C19H12F4O2S

References

– [1]Felts AS, et.al. Sulindac derivatives that activate the peroxisome proliferator-activated receptor gamma but lack cyclooxygenase inhibition. J Med Chem. 2008 Aug 28;51(16):4911-9.

CAS Number

– 1049800-41-0

Molecular Weight

– 380.36

SMILES

– OC(CC1=C/C(C2=CC=C(F)C=C21)=CC3=CC=C(C=C3)SC(F)(F)F)=O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– PPAR

Isoform

– PPARγ

Pathway

– Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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