Download Files:
Products Details
Product Description
– PP30, a TORKinib, is a potent, selective, and ATP-competitive inhibitor of mTOR with an IC50 of 80 nM.
Web ID
– HY-15269
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H19N7OS
References
– [1]Morris E Feldman, et al. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol. 2009 Feb 10;7(2):e38.
CAS Number
– 1092788-09-4
Molecular Weight
– 381.45
SMILES
– NC1=C2C(N(C(C)C)N=C2C3=CC(C(NC4=NCCS4)=O)=CC=C3)=NC=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– mTOR;PI3K
Isoform
– PI3Kγ;PI3Kδ
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
