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p,p’-DDE
$70 – $150
Products Details
Product Description
– p,p’-DDE (4,4′-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM[1].
Web ID
– HY-B1986
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C14H8Cl4
References
– [1]Kelce WR, et al. Persistent DDT metabolite p,p’-DDE is a potent androgen receptor antagonist. Nature. 1995;375(6532):581-585.
CAS Number
– 72-55-9
Molecular Weight
– 318.03
Compound Purity
– 99.50
SMILES
– Cl/C(Cl)=C(C1=CC=C(Cl)C=C1)/C2=CC=C(Cl)C=C2
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Androgen Receptor;Drug Metabolite
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
