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Products Details
Product Description
– p,p’-DDD-d8 is the deuterium labeled p,p’-DDD[1]. p,p’-DDD is a major metabolite of p,p’-DDT. p,p’-DDD occurs in the feces and livers of rats, that are given p,p’-DDT by stomach tube, but not of rats injected intraperitoneally with p,p’-DDT[2][3].
Web ID
– HY-B1984S
Shipping
– Room temperature
Molecular Formula
– C14H2D8Cl4
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Mendel JL, et al. Conversion of p,p’ -DDT to p,p’ -DDD by intestinal flora of the rat. Science. 1966;151(3717):1527-1528.|[3]Gerić M, et al. Cytogenetic status of human lymphocytes after exposure to low concentrations of p,p’-DDT, and its metabolites (p,p’-DDE, and p,p’-DDD) in vitro. Chemosphere. 201287(11):1288-1294.
CAS Number
– 93952-20-6
Molecular Weight
– 328.09
SMILES
– ClC(Cl)C(C1=C([2H])C([2H])=C(C([2H])=C1[2H])Cl)C2=C([2H])C([2H])=C(C([2H])=C2[2H])Cl
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Isotope-Labeled Compounds
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