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Products Details
Product Description
– POP-IN-2 (Compound 7k) is a potent, covalent prolyl oligopeptidase (POP) inhibitor with a Ki of 6 nM. POP-IN-2 can be used for studying neurodegenerative diseases and cancer[1].
Web ID
– HY-143475
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H33BN2O5
References
– [1]Jessica Plescia, et al. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur J Med Chem. 2020 Jan 1;185:111783.
CAS Number
– 2743432-81-5
Molecular Weight
– 440.34
SMILES
– CC(NC1=CC=C(C(N2C(B3O[C@@]4([H])[C@@]([C@](C5)([H])C(C)(C)[C@]5([H])C4)(C)O3)CCC2)=O)C(OC)=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Prolyl Endopeptidase (PREP)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
