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Pomalidomide-PEG1-C2-COOH
SKU
HY-137531-25 mg
Category Reference compound
Tags Cancer, E3 Ligase Ligand-Linker Conjugates, PROTAC
$190
Only 1000 item(s) left in stock.
Products Details
Product Description
– Pomalidomide-PEG1-C2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 1-unit PEG linker used in PROTAC technology[1].
Web ID
– HY-137531
Storage Temperature
– 4°C (Powder, stored under nitrogen, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H19N3O7
References
– [1]Qiu X, et al. Jiang B. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019;21(10):3838-3841.
CAS Number
– 2139348-60-8
Molecular Weight
– 389.36
Compound Purity
– 99.88
SMILES
– OC(CCOCCNC1=C(C(N(C2C(NC(CC2)=O)=O)C3=O)=O)C3=CC=C1)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
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