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Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH
$480
Only 1000 item(s) left in stock.
Products Details
Product Description
– Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
Web ID
– HY-128848
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C31H44N4O11
References
– [1]Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.
CAS Number
– 2351103-63-2
Molecular Weight
– 648.70
Compound Purity
– 95.02
SMILES
– O=C(NC1=O)CCC1N(C2=O)C(C3=C2C(NCCNC(COCCCCCOCCOCCCCCOCC(O)=O)=O)=CC=C3)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 55 mg/mL (ultrasonic)
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
