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Pomalidomide-amino-PEG3-NH2
SKU
HY-133817A-Get quote
Category Reference compound
Tags Cancer, E3 Ligase Ligand-Linker Conjugates, PROTAC
Products Details
Product Description
– Pomalidomide-amino-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Web ID
– HY-133817A
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H26N4O8
References
– [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.|[2]Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.
CAS Number
– 2380273-74-3
Molecular Weight
– 462.45
SMILES
– O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)COCCOCCOCCN
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
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