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Products Details
Product Description
– Pomalidomide-5′-C8-acid (Compound 3d’) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide-5′-C8-acid can be used in the synthesis of PROTACs[1].
Web ID
– HY-160017
Shipping
– Room temperature
Molecular Formula
– C22H27N3O6
References
– [1]Rao, Yu, et al. Preparation of isoindoline derivatives as degradation agent targeting both BTK and GSPT1 proteins and its application. Patent. CN115304606
CAS Number
– 2682112-09-8
Molecular Weight
– 429.47
SMILES
– O=C(CCCCCCCCNC1=CC=C2C(N(C3C(NC(CC3)=O)=O)C(C2=C1)=O)=O)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
