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Pomalidomide 4′-PEG5-acid
$400 – $650
Products Details
Product Description
– Pomalidomide 4′-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology[1].
Web ID
– HY-131647
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H35N3O11
References
– [1][1]Jing Liu, et al. Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use. WO2020173440A1.
CAS Number
– 2139348-63-1
Molecular Weight
– 565.57
Compound Purity
– 96.25
SMILES
– O=C(O)CCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– H2O : 50 mg/mL (ultrasonic)
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
