Pomalidomide 4′-PEG5-acid

$400$650

Products Details

Product Description

– Pomalidomide 4′-PEG5-acid (Pomalidomide-PEG5-CO2H) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 5-unit PEG linker used in PROTAC technology[1].

Web ID

– HY-131647

Storage Temperature

– -20°C (Powder, stored under nitrogen)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C26H35N3O11

References

– [1][1]Jing Liu, et al. Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use. WO2020173440A1.

CAS Number

– 2139348-63-1

Molecular Weight

– 565.57

Compound Purity

– 96.25

SMILES

– O=C(O)CCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– H2O : 50 mg/mL (ultrasonic)

Target

– E3 Ligase Ligand-Linker Conjugates

Isoform

– Cereblon

Pathway

– PROTAC

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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