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Polymyxin B
$30 – $60
Products Details
Product Description
– Polymyxin B is an antibiotic. Polymyxin B inhibits Gram-negative infections by binding to the LPS of the bacterial wall with high affinity. Polymyxin B neutralizes the effect of endotoxin. Polymyxin B induces bacterial death by increasing its permeability. Polymyxin B is used in endotoxemia research[1][3].
Web ID
– HY-149179
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– N/A
References
– [1]Martin EL, et al. Endotoxin removal: how far from the evidence? The EUPHAS 2 Project. Contrib Nephrol. 2010;167:119-125.|[2]Manchandani P, et al.Role of Renal Drug Exposure in Polymyxin B-Induced Nephrotoxicity. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02391-16. |[3]Cardoso LS, et al.Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis. Microb Cell Fact. 2007 Jan 3;6:1.
CAS Number
– 1404-26-8
Molecular Weight
– N/A
Compound Purity
– 91.0
SMILES
– [Polymyxin B]
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– H2O : 33.33 mg/mL (ultrasonic;adjust pH to 2 with HCl)
Target
– Antibiotic;Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
