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Products Details
Product Description
– Poly(A) polymerase catalyzes the incorporation of ATP into the RNA 3′ end in the form of AMP, that is, adding a polyadenosine tail at the RNA 3′ end. Poly(A) polymerase increases RNA stability and increases mRNA translation efficiency in eukaryotic cells. Poly(A) polymerase has high tailing efficiency and can add 20-200 A bases to the 3′ end of RNA[1][2].
Web ID
– HY-E70099
Storage Temperature
– -20°C
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– N/A
References
– [1]Li W, et al. The novel poly(A) polymerase Star-PAP is a signal-regulated switch at the 3′-end of mRNAs. Adv Biol Regul. 2013 Jan;53(1):64-76. |[2]Chen LS, et al. Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues. Biochem Pharmacol. 2010 Mar 1;79(5):669-77.
CAS Number
– 9026-30-6
Molecular Weight
– N/A
SMILES
– [Poly(A) polymerase]
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Biochemical Assay Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
