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Poliumoside
$139 – $1,070
Products Details
Product Description
– Poliumoside, a caffeoylated phenylpropanoid glycoside, is isolated from Brandisia hancei stems and leaves. Poliumoside is an advanced glycation end product (AGE) formation and rat lens aldose reductase (RLAR) inhibitor, with IC50s of 19.69 and 8.47 μM, respectively. Poliumoside also has antiinflammatory and antioxidant activity[1][2][3].
Web ID
– HY-N0033
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C35H46O19
References
– [1]He ZD, et, al. Antioxidant activity of phenylethanoid glycosides from Brandisia hancei. J Ethnopharmacol. 2000 Aug;71(3):483-6.|[2]Wu A, et, al. Natural phenylethanoid glycosides isolated from Callicarpa kwangtungensis suppressed lipopolysaccharide-mediated inflammatory response via activating Keap1/Nrf2/HO-1 pathway in RAW 264.7 macrophages cell. J Ethnopharmacol. 2020 Aug 10;258:112857.|[3]Yu SY, et al. Caffeoylated phenylpropanoid glycosides from Brandisia hancei inhibit advanced glycation end product formation and aldose reductase in vitro and vessel dilation in larval zebrafish in vivo. Planta Med. 2013 Dec;79(18):1705-9.
CAS Number
– 94079-81-9
Molecular Weight
– 770.73
Compound Purity
– 99.80
SMILES
– OC1=C(O)C=CC(CCOC2C(C(OC3OC(C)C(O)C(O)C3O)C(OC(/C=C/C4=CC=C(O)C(O)=C4)=O)C(COC5OC(C)C(O)C(O)C5O)O2)O)=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)|Ethanol : 50 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
Target
– Aldose Reductase
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
