Download Files:
Pociredir (hydrochloride)
$1,480 – $12,500
Products Details
Product Description
– Pociredir (FTX-6058) hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). Pociredir hydrochloride can induce HbF protein expression in cell and murine models. Pociredir hydrochloride can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2].
Web ID
– HY-139400A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H19ClFN5O2
References
– [1]Boerner LK. Virtual meeting delivers first time drug structures. April 12, 2021.|[2]Fulcrum Therapeutics Presents Published Structure of Investigational Small Molecule FTX-6058 at the American Chemical Society (ACS) Spring 2021 Virtual Conference.
CAS Number
– 2490676-19-0
Molecular Weight
– 439.87
Compound Purity
– 99.83
SMILES
– CC1=NC=CC=C1C2=CC(OC3)=C(NCC4=C(F)C=CC5=C4[C@@H]3CO5)N6C2=NN=C6.[H]Cl
Clinical Information
– Phase 1
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Histone Methyltransferase
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
