Pociredir

$1,480$2,450

Products Details

Product Description

– Pociredir (FTX-6058) is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). Pociredir can induce HbF protein expression in cell and murine models. Pociredir can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia[1][2].

Web ID

– HY-139400

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C22H18FN5O2

References

– [1]Boerner LK. Virtual meeting delivers first time drug structures. April 12, 2021.|[2]Fulcrum Therapeutics Presents Published Structure of Investigational Small Molecule FTX-6058 at the American Chemical Society (ACS) Spring 2021 Virtual Conference.

CAS Number

– 2490676-18-9

Molecular Weight

– 403.41

Compound Purity

– 99.97

SMILES

– CC1=NC=CC=C1C2=CC(OC3)=C(NCC4=C(F)C=CC5=C4[C@@H]3CO5)N6C2=NN=C6

Clinical Information

– Phase 1

Research Area

– Cardiovascular Disease

Solubility

– DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Histone Methyltransferase

Pathway

– Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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