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Products Details
Product Description
– Plm IV inhibitor-2 (compound 3) is a potent digestive vacuole plasmepsins IV (Plm IV) inhibitor with IC50 values of 24 nM, 70 nM and 0.3 μM for Plm IV, II and I, respectively. Plm IV inhibitor-2 can be used to research malaria caused by Plasmodium parasites[1].
Web ID
– HY-148035
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C39H54N4O4
References
– [1]Jaudzems K, et al. Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit. ACS Med Chem Lett. 2014 Jan 13;5(4):373-7.
CAS Number
– 1539276-38-4
Molecular Weight
– 642.87
SMILES
– CCCN(CCC)C(C1=CC(C(N[C@H]([C@H](O)CNC(C)(C2=CC(OC)=CC=C2)C)CC3=CC=CC=C3)=O)=CC(N4CCCCC4)=C1)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Isoform
– Plasmodium
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
