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Products Details
Product Description
– PLK4-IN-3 is a less active absolute stereochemistry of PLK4-IN-1. PLK4-IN-1 is a PLK4 inhibitor, with an IC50 of 0.65 μM[1].
Web ID
– HY-134775A
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H14IN3O2
References
– [1]Peter Brent Sampson, et al. KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME. Patent. WO2011123946A1.
CAS Number
– 1247001-86-0
Molecular Weight
– 431.23
SMILES
– O=C([C@@]12[C@H](C3=CC4=C(C=C3)C(I)=NN4)C1)NC5=C2C=C(OC)C=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Polo-like Kinase (PLK)
Isoform
– PLK4
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
