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Products Details
Product Description
– PLK1-IN-7 (compound 30e) is a potent PLK1 inhibitor, with an IC50 of 0.66 nM. PLK1-IN-7 exhibits antiproliferative and antitumor activities[1].
Web ID
– HY-156336
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H24F4N8O2
References
– [1]Lu J, et, al. Design, synthesis, and biological evaluation of novel molecules as potent inhibitors of PLK1. Bioorg Chem. 2023 Oct:139:106711.
CAS Number
– 2938910-96-2
Molecular Weight
– 532.49
SMILES
– FC(F)(OC(C=CC(N1CCN(C)CC1)=C2)=C2NC3=NC=C4C(C5=C(C=C4)C(C(N)=O)=NN5CCF)=N3)F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Polo-like Kinase (PLK)
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
