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Products Details
Product Description
– PLK1-IN-5 is a potent PLK1 inhibitor with an IC50 of < 500 nM. PLK1-IN-5 shows anticancer effects (WO2008113711A1; compound I-4)[1].
Web ID
– HY-148974
Shipping
– Room temperature
Molecular Formula
– C28H39N7O3
References
– [1]Jianping Cai, et al. Substituted pyrimidodiazepines useful as plk1 inhibitors. WO2008113711A1.
CAS Number
– 1001343-34-5
Molecular Weight
– 521.65
SMILES
– O=C(C1=CC=C(C(OC)=C1)NC2=NC=C3C(N(C4CCCC4)C(CC(N3C)=O)C)=N2)NC5CCN(CC5)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Polo-like Kinase (PLK)
Isoform
– PLK1
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
