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Products Details
Product Description
– PLK1-IN-2 is a PLK1 kinase inhibitor with an IC50 value of 0.384 μM.
Web ID
– HY-139652
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H27FN8OS
References
– [1]Kargbo RB. Modulation of KRAS Mutant by Inhibiting PLK1 Kinase in Cancer Therapeutics. ACS Med Chem Lett. 2021 Sep 15;12(10):1514-1516.
CAS Number
– 2640254-52-8
Molecular Weight
– 494.59
SMILES
– CN(CC1)CCN1C2=CC=C(NC3=NC(N(C4=NC(N=S(C)(C)=O)=CC=C4)C=C5F)=C5C=N3)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Polo-like Kinase (PLK)
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
