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Plicamycin
SKU
HY-A0122-1 mg
Category Reference compound
Tags Anti-infection;Cell Cycle/DNA Damage, Antibiotic;Bacterial;DNA/RNA Synthesis, Cancer; Infection
$170 – $4,550
Products Details
Product Description
– Plicamycin is a selective specificity protein 1 (Sp1) inhibitor. Plicamycin inhibits the growth of various cancers by decreasing Sp1 protein.
Web ID
– HY-A0122
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C52H76O24
References
– [1]Choi ES, et al. Modulation of specificity protein 1 by mithramycin A as a novel therapeutic strategy for cervical cancer. Sci Rep. 2014 Nov 24;4:7162.
CAS Number
– 18378-89-7
Molecular Weight
– 1085.15
Compound Purity
– 99.60
SMILES
– O=C([C@H]([C@@]([C@H](OC)C([C@@H](O)[C@H](O)C)=O)([H])C1)O[C@@](O[C@H](C)[C@H]2O)([H])C[C@H]2O[C@@](O[C@H](C)[C@@H]3O)([H])C[C@H]3O[C@@](O[C@H](C)[C@H]4O)([H])C[C@@]4(O)C)C(C1=CC5=CC(O[C@H](O[C@H](C)[C@H]6O)C[C@H]6O[C@@](O[C@H](C)[C@H]7O)([H])C[C@H]7O)=C(C)C(O)=C85)=C8O
Clinical Information
– Launched
Research Area
– Cancer; Infection
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Antibiotic;Bacterial;DNA/RNA Synthesis
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.