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Plicamycin

$170$4,550

Products Details

Product Description

– Plicamycin is a selective specificity protein 1 (Sp1) inhibitor. Plicamycin inhibits the growth of various cancers by decreasing Sp1 protein.

Web ID

– HY-A0122

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C52H76O24

References

– [1]Choi ES, et al. Modulation of specificity protein 1 by mithramycin A as a novel therapeutic strategy for cervical cancer. Sci Rep. 2014 Nov 24;4:7162.

CAS Number

– 18378-89-7

Molecular Weight

– 1085.15

Compound Purity

– 99.60

SMILES

– O=C([C@H]([C@@]([C@H](OC)C([C@@H](O)[C@H](O)C)=O)([H])C1)O[C@@](O[C@H](C)[C@H]2O)([H])C[C@H]2O[C@@](O[C@H](C)[C@@H]3O)([H])C[C@H]3O[C@@](O[C@H](C)[C@H]4O)([H])C[C@@]4(O)C)C(C1=CC5=CC(O[C@H](O[C@H](C)[C@H]6O)C[C@H]6O[C@@](O[C@H](C)[C@H]7O)([H])C[C@H]7O)=C(C)C(O)=C85)=C8O

Clinical Information

– Launched

Research Area

– Cancer; Infection

Solubility

– DMSO : ≥ 100 mg/mL

Target

– Antibiotic;Bacterial;DNA/RNA Synthesis

Pathway

– Anti-infection;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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