Download Files:
Products Details
Product Description
– Plasma kallikrein-IN-1 is a PKK inhibitor with an IC50 value of 0.5 nM.
Web ID
– HY-139888
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C23H25F2N7O
References
– [1]Sabnis RW. Novel Heteroaromatic Carboxamides as Plasma Kallikrein Inhibitors for Treating Diabetic Complications, Ocular Diseases, and Edema-Associated Diseases. ACS Med Chem Lett. 2021 Oct 21;12(11):1637-1638.
CAS Number
– 2691030-28-9
Molecular Weight
– 453.49
SMILES
– FC(F)C1=C(C=CC(N2CC3(CC3)C2)=N1)CN4C=NC(C(N[C@@H]5CCC6=C(C)NN=C65)=O)=C4
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– Ser/Thr Protease
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
