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PKUMDL-LC-101-D04
$100 – $1,580
Products Details
Product Description
– PKUMDL-LC-101-D04 (GPX4-Activator-1d4) is a potent ferroptosis regulator glutathione peroxidase 4 (GPX4) allosteric activator (pEC50=4.7). PKUMDL-LC-101-D04 increases GPX4 activity to 150% at 20 μM in the cell-free assay and 61 μM in cell extracts[1].
Web ID
– HY-115627
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H23ClN4O2S2
References
– [1]Li C, et al. Novel Allosteric Activators for Ferroptosis Regulator Glutathione Peroxidase 4. J Med Chem. 2019;62(1):266-275.
CAS Number
– 2143896-83-5
Molecular Weight
– 378.94
Compound Purity
– 99.43
SMILES
– O=S(C1=CC=C(NC(NC2CCCC2)=S)C=C1)(NCCN)=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Glutathione Peroxidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
