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Products Details
Product Description
– PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC50=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL)[1].
Web ID
– HY-151204
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H30N2O2
References
– [1]Paptawan Thongdee, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22.
CAS Number
– 1447917-39-6
Molecular Weight
– 390.52
SMILES
– CCCCN(CC(CN1C=C(C2=C1C=CC=C2)/C=C/C(C3=CC=CC=C3)=O)O)C
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
