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Products Details
Product Description
– PITB is a selective and orally active transthyretin (TTR) aggregation inhibitor. PITB can be used for transthyretin amyloidosis (ATTR) disease research[1].
Web ID
– HY-155299
Shipping
– Room temperature
Molecular Formula
– C14H10FNO6
References
– [1]Francisca Pinheiro, et al. PITB: A high affinity transthyretin aggregation inhibitor with optimal pharmacokinetic properties. Eur J Med Chem. 2023 Oct 6:261:115837.
Molecular Weight
– 307.23
SMILES
– O=C(C1=CC(O)=CC(F)=C1)C2=CC(OC)=C(O)C([N+]([O-])=O)=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Transthyretin (TTR)
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
