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Pirenperone
SKU
HY-B1737-1 mg
Category Reference compound
Tags 5-HT Receptor, GPCR/G Protein;Neuronal Signaling, Neurological Disease
$45 – $460
Products Details
Product Description
– Pirenperone (R 47465) is a 5-HT2 serotonin receptor antagonist. Pirenperone exhibits modest anxiolytic activity[1][2].
Web ID
– HY-B1737
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H24FN3O2
References
– [1]Krstić MK, et, al. Divergent effects of pirenperone, a 5-HT2 antagonist, on the pressor and tachycardic responses to 5-HT in guinea-pigs. Arch Int Physiol Biochim. 1983 Nov;91(4):345-9. |[2]Ansseau M, et, al. Pilot study of a specific serotonergic antagonist, pirenperone, in the treatment of anxiety disorders. Acta Psychiatr Belg. Sep-Oct 1983;83(5):517-24.
CAS Number
– 75444-65-4
Molecular Weight
– 393.45
Compound Purity
– 98.74
SMILES
– O=C1C(CCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)=C(C)N=C4N1C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 0.1 M HCL : 16.67 mg/mL (ultrasonic;warming;adjust pH to 3 with 0.1 M HCL;heat to 60°C)|DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– 5-HT Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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