Download Files:
Products Details
Product Description
– Piperaquine-d6 (tetraphosphate) is the deuterium labeled Piperaquine tetraphosphate. Piperaquine tetraphosphate is a bisquinoline antimalarial agent. Piperaquine phosphate can be used in antimalarial research in combination with Artemisinin[1][2].
Web ID
– HY-118865S
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C29H38D6Cl2N6O16P4
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Moore BR, et, al. Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model. Antimicrob Agents Chemother. 2008 Jan; 52(1): 306-11.|[3]Davis TME, et, al. Piperaquine: a resurgent antimalarial drug. Drugs. 2005; 65(1): 75-87.
Molecular Weight
– 933.53
SMILES
– ClC1=CC2=C(C=C1)C(N3CCN(CC3)C([2H])([2H])C([2H])([2H])C([2H])([2H])N4CCN(C5=CC=NC6=C5C=CC(Cl)=C6)CC4)=CC=N2.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Isotope-Labeled Compounds;Parasite
Isoform
– Plasmodium
Pathway
– Anti-infection;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
