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Products Details
Product Description
– PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC50 = 61 nM; pS6, EC50 = 71 nM).
Web ID
– HY-142656
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C15H18ClFN4O
References
– [1]Barberis C, et al. Discovery of SARxxxx92, a pan-PIM kinase inhibitor, efficacious in a KG1 tumor model. Bioorg Med Chem Lett. 2020 Dec 1;30(23):127625.
CAS Number
– 2698319-19-4
Molecular Weight
– 324.78
SMILES
– O=C(C1=CC(Cl)=C2C(N([C@@H]([C@]3(F)CNCC3)C)C=C2C)=N1)N
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Pim
Pathway
– JAK/STAT Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
