Products Details

Product Description

– PIM-IN-1 is a pan-PIM kinase inhibitor (KG-1, EC50 = 61 nM; pS6, EC50 = 71 nM).

Web ID

– HY-142656

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C15H18ClFN4O

References

– [1]Barberis C, et al. Discovery of SARxxxx92, a pan-PIM kinase inhibitor, efficacious in a KG1 tumor model. Bioorg Med Chem Lett. 2020 Dec 1;30(23):127625.

CAS Number

– 2698319-19-4

Molecular Weight

– 324.78

SMILES

– O=C(C1=CC(Cl)=C2C(N([C@@H]([C@]3(F)CNCC3)C)C=C2C)=N1)N

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Pim

Pathway

– JAK/STAT Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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