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Products Details
Product Description
– Pim-1 kinase inhibitor 3 (Compound H5) is a potent Pim-1 kinase inhibitor with an IC50 of 35.13 nM[1].
Web ID
– HY-150731
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H25N3O2
References
– [1]Xu J, et al. Design, synthesis, and bioactivity evaluation of macrocyclic benzo[b]pyrido[4,3-e][1,4]oxazine derivatives as novel Pim-1 kinase inhibitors. Bioorg Med Chem Lett. 2022 Sep 15;72:128874.
CAS Number
– 2801695-39-4
Molecular Weight
– 339.43
SMILES
– C12=CC3=C(C=C2)OC4=C(C=CN=C4)N3CCCCCNCCCCO1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Pim
Isoform
– PIM1
Pathway
– JAK/STAT Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
