Download Files:
Pichromene
$158
Only 1000 item(s) left in stock.
Products Details
Product Description
– Pichromene (S14161) is an anticancer agent and weak PI3K inhibitor. Pichromene can effectively inhibit tumor growth in leukemia mouse models and can be used in cancer research[1][2].
Web ID
– HY-111209
Shipping
– Room temperature
Molecular Formula
– C17H14FNO4
References
– [1]Mao X, et al. A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway. Blood. 2011 Feb 10;117(6):1986-97.|[2]Fouqué A, et al. A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells. J Med Chem. 2015 Aug 27;58(16):6559-73.
CAS Number
– 883046-50-2
Molecular Weight
– 315.30
SMILES
– O=[N+](C1=CC2=CC=CC(OCC)=C2OC1C3=CC=C(F)C=C3)[O-]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PI3K
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
