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Products Details
Product Description
– PI3Kdelta inhibitor 1 (Compound 5d) is a potent, selective and orally available PI3Kδ inhibitor with an IC50 of 1.3 nM[1].
Web ID
– HY-112439
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H38N6O5S
References
– [1]Hamajima T, et al. Optimization and in vivo evaluation of pyrazolopyridines as a potent and selective PI3Kδ inhibitor. Bioorg Med Chem. 2018 Aug 7;26(14):3917-3924.
CAS Number
– 2242109-74-4
Molecular Weight
– 558.69
SMILES
– CN1C2=NC(C3=CC(NS(C)(=O)=O)=C(OC)N=C3)=CC(OC[C@H]4CN(CCC5CCOCC5)CCC4)=C2C=N1
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– PI3K
Isoform
– PI3Kδ
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
