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Products Details
Product Description
– PI3K/mTOR Inhibitor-5 (compound 19a) is a potent and dual PI3K and mTOR inhibitor, with IC50 values of 86.9 nM and 14.6 nM, respectively[1].
Web ID
– HY-146016
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C32H40N10O3
References
– [1]Wu TT, Guo QQ, Chen ZL, et al. Design, synthesis and bioevaluation of novel substituted triazines as potential dual PI3K/mTOR inhibitors. Eur J Med Chem. 2020;204:112637.
CAS Number
– 2456295-60-4
Molecular Weight
– 612.73
SMILES
– O=C(N1CCC(N(C)C)CC1)C2=CC=C3N=C(NC4=CC=C(C5=NC(N6CCOCC6)=NC(N7CCOCC7)=N5)C=C4)NC3=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– mTOR;PI3K
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
