PI3K/mTOR Inhibitor-14

SKU HY-156445-Get quote Category Tags , ,

Products Details

Product Description

– PI3K/mTOR Inhibitor-14 (compound Y-2) is a potent PI3K and mTOR dual inhibitor with IC50s of 171.4 nM and 10.1 nM, respectively. PI3K/mTOR Inhibitor-14 has antitumor activities[1].

Web ID

– HY-156445

Shipping

– Room temperature

Molecular Formula

– C28H30N8O3S

References

– [1]Yang Yang, et al. Discovery of novel potent PI3K/mTOR dual-target inhibitors based on scaffold hopping: Design, synthesis, and antiproliferative activity. Arch Pharm (Weinheim). 2023 Oct 15:e2300403.

CAS Number

– 2919684-77-6

Molecular Weight

– 558.65

SMILES

– O=C(NC1=CC=C(C2=NC(N3CCOCC3)=NC(C4=CC=C(CN5CCOCC5)S4)=N2)C=C1)NC6=CC=CN=C6

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– mTOR;PI3K

Isoform

– mTOR;PI3K

Pathway

– PI3K/Akt/mTOR

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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