Products Details

Product Description

– PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1].

Web ID

– HY-150034

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C20H24N6O2

References

– [1]Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1.

CAS Number

– 1382979-64-7

Molecular Weight

– 380.44

SMILES

– CC1(C)OCCN2C1=NC3=C(N4CCOCC4)N=C(C5=CC=C(N)C=C5)N=C23

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– PI3K

Isoform

– PI3Kα

Pathway

– PI3K/Akt/mTOR

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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