Download Files:
Products Details
Product Description
– PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1].
Web ID
– HY-150034
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H24N6O2
References
– [1]Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1.
CAS Number
– 1382979-64-7
Molecular Weight
– 380.44
SMILES
– CC1(C)OCCN2C1=NC3=C(N4CCOCC4)N=C(C5=CC=C(N)C=C5)N=C23
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– PI3K
Isoform
– PI3Kα
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
