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Products Details
Product Description
– PI3Kγ inhibitor 5 is an inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with an IC50 value of 34 nM.
Web ID
– HY-139880
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C28H32F2N6O4
References
– [1]Mata G, et al. Design, Synthesis, and Structure-Activity Relationship Optimization of Pyrazolopyrimidine Amide Inhibitors of Phosphoinositide 3-Kinase γ (PI3Kγ). J Med Chem. 2021 Oct 21.
CAS Number
– 2566569-31-9
Molecular Weight
– 554.59
SMILES
– O=C(C1=C2N=C(C3=CC4=C(C(N([C@H](C5CC5)C)C4)=O)C(OC(F)F)=C3)C=CN2N=C1N)N[C@H]6CC[C@@](C)(O)CC6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PI3K
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
