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Phosphoramide mustard (cyclohexanamine)
$340 – $3,200
Products Details
Product Description
– Phosphoramide mustard cyclohexanamine is a biologically active metabolite of Cyclophosphamide (HY-17420), with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA damage[1][2].
Web ID
– HY-137316A
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C10H24Cl2N3O2P
References
– [1]Shanthi Ganesan, et al. Phosphoramide mustard exposure induces DNA adduct formation and the DNA damage repair response in rat ovarian granulosa cells. Toxicol Appl Pharmacol. 2015 Feb 1; 282(3): 252–258.|[2]S Genka, et al. Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoramide mustard in the rat. Cancer Chemother Pharmacol. 1990;27(1):1-7.
CAS Number
– 1566-15-0
Molecular Weight
– 320.20
Compound Purity
– 95.0
SMILES
– O=P(N(CCCl)CCCl)(N)O.NC1CCCCC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– H2O : 100 mg/mL (ultrasonic)
Target
– DNA Alkylator/Crosslinker;Drug Metabolite
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
