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Products Details
Product Description
– Phosphodiesterase-IN-1 (Compound 7) is a phosphodiesterase (PDE) inhibitor with anti-Plasmodium activity. Phosphodiesterase-IN-1 has antiproliferative activity against P. falciparum (strain 3D7) with an IC50 value of 0.64 μM[1].
Web ID
– HY-149782
Shipping
– Room temperature
Molecular Formula
– C15H15FN4O
References
– [1]Howard BL, et al. Identification of potent phosphodiesterase inhibitors that demonstrate cyclic nucleotide-dependent functions in apicomplexan parasites. ACS Chem Biol. 2015 Apr 17;10(4):1145-54.
CAS Number
– 521297-42-7
Molecular Weight
– 286.30
SMILES
– O=C1N=C(CC2=CC=C(C=C2)F)NC3=C1NN=C3C(C)C
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite;Phosphodiesterase (PDE)
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
