Download Files:
Products Details
Product Description
– Phenacaine (Holocaine) is a local anesthetic. Phenacaine inhibits the specific calmodulin-dependent stimulation of erythrocyte Ca2+-ATPase and cyclic nucleotide phosphodiesterases from brain and heart[1][2].
Web ID
– HY-B1726
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C18H22N2O2
References
– [1]M Volpi, et al. Local anesthetics, mepacrine, and propranolol are antagonists of calmodulin. Proc Natl Acad Sci U S A. 1981 Feb;78(2):795-9. |[2]R Bressler, et al. Effect of local anesthetics on insulin secretion by pancreas pieces. Diabetes. 1971 Nov;20(11):721-8.
CAS Number
– 101-93-9
Molecular Weight
– 298.38
SMILES
– C/C(NC1=CC=C(OCC)C=C1)=NC2=CC=C(OCC)C=C2
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
