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Products Details
Product Description
– Phe-Lys(Trt)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
Web ID
– HY-129349
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C41H44N4O3
References
– [1]Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.
CAS Number
– 1116085-99-4
Molecular Weight
– 640.81
SMILES
– O=C(N)[C@H](CCCCNC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)N(C([C@H](CC4=CC=CC=C4)N)=O)C5=CC=C(CO)C=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Cleavable Linker;Protease Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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