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Products Details
Product Description
– PHD-IN-2 (Compound 91) is a PHD antagonist (IC50: < 5 nM). PHD-IN-2 induces erythropoietin synthesis in HEP3B cells (EC50: <2.5 μM). PHD-IN-2 can be used for research of cardiovascular disorders, metabolic disorders, hematological disorders, pulmonary disorders, kidney disorders, liver disorders, wound healing disorders, and cancer[1].
Web ID
– HY-156527
Shipping
– Room temperature
Molecular Formula
– C26H27N7O4
References
– [1]Xiao DING, et al. Prolyl hydroxylase domain-containing protein (phd) inhibitors and uses thereof. Patent. US20230192723A1.
CAS Number
– 2924182-42-1
Molecular Weight
– 501.54
SMILES
– N#CC1=NC=C(CNC(C2=NC=C3N=C(N4CC5(C4)CN(C5)C(OC(C)(C)C)=O)C=CC3=C2O)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
