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PGlu-3-methyl-His-Pro-NH2 (TFA)
$220 – $720
Products Details
Product Description
– PGlu-3-methyl-His-Pro-NH2 TFA (A-42872 TFA), the modified thyrotropin-releasing hormone (TRH) peptide, enhances binding to pituitary TRH receptors and increases stimulation of thyroid-stimulating hormone (TSH) release from the pituitary. The in vitro permeability of PGlu-3-methyl-His-Pro-NH2 TFA through rat skin is increased in the presence of enhancers Ethanol and Cineole[1][2].
Web ID
– HY-107380A
Storage Temperature
– -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Molecular Formula
– C19H25F3N6O6
References
– [1]Koskinen LO, et al. Cerebrovascular effects of the TRH analogues pGlu-3-methyl-His-Pro amide and pGlu-Glu-Pro amide: a comparison with TRH. Ups J Med Sci. 2000;105(1):73-83.|[2]Magnusson BM, et al. Biological effects after percutaneous absorption of thyrotropin-releasing hormone and its analogue M-TRH. Peptides. 2001 Jan;22(1):73-9.
Molecular Weight
– 490.43
Compound Purity
– 99.69
SMILES
– CN1C(C[C@H](NC([C@@H](N2)CCC2=O)=O)C(N3[C@@H](CCC3)C(N)=O)=O)=CN=C1.OC(C(F)(F)F)=O
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 250 mg/mL (ultrasonic)
Target
– Others
Pathway
– Others
Product type
– Peptides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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