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Products Details
Product Description
– PG01037 (dihydrochloride) is a potent and selective dopamine D3 receptor antagonist with a Ki of 0.7 nM[1].
Web ID
– HY-103408
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H28Cl4N4O
References
– [1]Grundt P, et al. Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. J Med Chem. 2005 Feb 10;48(3):839-48.
CAS Number
– 675599-62-9
Molecular Weight
– 554.34
SMILES
– O=C(NC/C=C/CN1CCN(C2=CC=CC(Cl)=C2Cl)CC1)C3=CC=C(C4=NC=CC=C4)C=C3.[H]Cl.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Isoform
– D3 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
